Vitamin D3 breakthrough halves risk of second heart attack

(sciencedaily.com)

45 points | by Noaidi a day ago ago

11 comments

  • mayanraisins a day ago ago

    My grandma went to the ER due to feeling nauseous and confused and they concluded it was Vitamin D toxicity from supplementation. She heard online that it’d help her avoid catching the flu.

    Just a reminder that you should get a blood test and advice from a medical professional before taking anything above the daily recommended amount.

    • Noaidi a day ago ago

      I agree 100%. But even with a blood test you need to be careful! I was taking 1000iu (doctors orders after a blood test) for about a month and it made my calcium spike above the normal range. I have freaky genes when it comes to Vitamin D and should have been taking more Vitamin K7 with it. But I now get it all from seafood, mostly salmon, since salmon also contains calcitonin [1].

      [1] Evidence that calcitonin stimulates 1,25-dihydroxyvitamin D production and intestinal absorption of calcium in vivo.

      https://pmc.ncbi.nlm.nih.gov/articles/PMC423580/

  • thisislife2 a day ago ago

    They were only prescribed 5000 IU? I was prescribed a dosage of 60,000 IU to treat my Vit. D deficiency!

    • wbsss4412 a day ago ago

      60,000 IU per day or per week?

      5,000 IU is most likely a daily dosage in this instance.

      • thisislife2 a day ago ago

        It was indeed per week, for 8 weeks. If it is 5000 IU, how many days do they usually prescribe it for?

        • DiabloD3 a day ago ago

          Most likely the rest of their life.

          5000 IU is largely the minimum effective dose for supplementation. The FDA still recommends less than half of this, and it is a shame.

          Disclaimer: I take 5k IU a day due to the past 2 decades of research on the efficacy.

          • thisislife2 a day ago ago

            A doctor who has written a good series of article on Vitamin D advises to be cautious about taking it "for life" - https://www.devaboone.com/post/vitamin-d-part-2-shannon-s-st... ... See also How long does it take for vitamin D to work? - https://www.drugs.com/medical-answers/long-vitamin-d-work-35...

            • DiabloD3 a day ago ago

              The first link aligns with what I know about it: above 70 ng/ml is where side effects start happening. I stay below 70 with 5000, but for other people, they may need less or even more, depends entirely on where you live, and other factors that are known to burn through Vitamin D (such as being overweight or drinking caffeinated beverages or experiencing high stress).

              Based research I've seen, for optimal wakefulness and cognitive ability, 50-60 is optimal, below 40 is too low, above 70 is too high.

              You may have to adjust dosage over time to dial this in.

          • hed a day ago ago

            It's amazing to get tested and thinking you're heavy dosing and when tests come back it turns out you're barely in the green (low).

            • thisislife2 a day ago ago

              In my case, with 8 doses of 60,000 IU / week, I am no longer deficient, but the blood test in the 9th week also revealed that I have slightly crossed the margin of safe levels (borderline toxicity) for Vitamin D.

          • jelsisi a day ago ago

            Is this how you chose your username?