Scientists discover oldest poison, on 60k-year-old arrows

(nytimes.com)

139 points | by noleary 2 days ago ago

67 comments

  • icyfox a day ago ago

    At the risk of being overly pedantic, topologists would typically classify this as venom.

    Venom is inert if digested; it's only a problem if it gets in your blood stream. So arrows that were laced with venom and thereby contaminated meat were actually perfectly safe to eat.

    Poison is different. If ingested, inhaled, or absorbed it will kill you.

    • skrebbel 21 hours ago ago

      We Dutch solve this problem by having a single word for "poison", "venom and "toxin"¹. Everybody still knows what you mean and nobody gets to be pedantic.

      ¹ and "badly compressed looping animation"

      • pjmlp 5 hours ago ago

        Same in Portuguese, veneno.

        Although there are plenty of other opportunities for pedantry, especially when we take regionalisms, and other Portuguese speaking countries into account.

      • OptionOfT 18 hours ago ago

        Vergif.

        I don't know how you get from 'ver' to badly compressed.

        (And I'm a native Flemish speaker, but living in the USA for 8+ years, so I barely, if ever speak it).

        • tharkun__ 17 hours ago ago

          Remove Ver, add t and you got German: Gift

          Vergiftet would be past tense.

          Funny that in English gift is a word but entirely different meaning.

          Languages are fun, especially in Europe where they're all different but all so related but everyone does not want to admit it.

          • animal531 10 hours ago ago

            It's probably the same, for example in Afrikaans its just gif. Vergif is the verb action of doing it, and vergiftig the same past tense of it having happened previously.

          • thaumasiotes 7 hours ago ago

            > Funny that in English gift is a word but entirely different meaning.

            In English it maintains its original Germanic meaning derived from the verb give.

            The sense of "poison" in German comes from a euphemistic use of "gift". (Literally 'something given' but actually used to calque Greek "dosis", which also literally meant 'something given', but was used to mean 'dose [of medicine]'.)

            https://en.wiktionary.org/wiki/Gift#Etymology

            Summing up, the reason gift is a word in English with an entirely different meaning from what it has in German is that everyone in Germany forgot what gift meant.

            (The reason it's gift and not something more like yift is the Danelaw.)

            • tharkun__ 4 hours ago ago

              This is one of the reasons I like HN: Random knowledge transfer like this. Appreciated!

              Also: in German Dosis is the word for dose.

                  Die Dosis macht das Gift
              
              (the dose makes the poison)
          • stevekemp 8 hours ago ago

            > all so related but everyone does not want to admit it.

            I'm laughing in Finnish..

            • tharkun__ 4 hours ago ago

              Hehe, you found the exception that proves the rule :P

              • SllX 3 hours ago ago

                And Basque, Maltese, Turkish and Georgian.

                Magyar (Hungarian) and Finnish are both Uralic languages along with Estonian and the Sámi languages, but none of these are related to the Indo-European languages common in the other parts of Europe.

                And while most of Europe’s extant languages are in the Indo-European language family, there’s still a fair number of differences between Albanian, Germanic, Hellenic, Celtic, Romantic and Slavic languages.

                • tharkun__ an hour ago ago

                  Oh for sure there are many differences, that comes with them being different languages, countries, ethnicity. You can do this on many levels.

                  The point was essentially what you're showing here: People focusing on all the differences instead of shared history, languages influencing each other and how we're all not that different in the end.

                  If you want to, even within what are nowadays countries and what outsiders would say is "one language" and "one ethnicity", you can start focusing on differences and make people dislike each other.

          • birdsongs 10 hours ago ago

            In Norwegian, "gift" is poison. It's also the word for married (de er gift).

            • pantalaimon 6 hours ago ago

              In German "Mitgift" is what the bride gets from her family when she enters marriage.

        • bruce343434 9 hours ago ago

          In NL, just 'gif' is sufficient

      • XCSme 20 hours ago ago

        Is the word "stamppot" ?

        • usrnm 12 hours ago ago

          Just "food". Any kind of Dutch food fits the description.

          • skrebbel 11 hours ago ago

            This is true, notably a kroket is both looping and badly compressed.

      • samlinnfer 19 hours ago ago

        Same in Chinese (毒). But it is a better solution just not to give pedants the time of the day.

      • gambiting 20 hours ago ago

        Same in Polish. You'd just call both of these "trucizna".

        • mbel 19 hours ago ago

          Not really, we have both „jad” (venom) and „trucizna” (poison).

          • usrnm 12 hours ago ago

            And in Russian we use "jad" ("яд" in cyrillic) for both. Although there is the word "отрава", which can be used for poisons and "яд" is closer to "venom" the difference is almost non-existant and both are often used interchangeably.

          • gtech1 17 hours ago ago

            How does this happen ? The poster above you isn't really Polish ? How can someone that claims to know Polish not know there's two different words ?

            • gambiting 11 hours ago ago

              Obviously I know "jad" but I don't see any issue with calling venom "trucizna". Natural languages aren't C++ and you don't get compiler errors when you speak - to me, there is no issue calling both venoms and poison trucizna. Polish dictionary doesn't seem to contradict it either:

              https://sjp.pwn.pl/slowniki/trucizna.html

              The point is, both are correct(afaik) while in English venom and poison are definitely two different things.

              • mbel 11 hours ago ago

                Nobody would say „trujący wąż” (poisonous snake) or „jadowity grzyb” (venomous mushroom). The distinction is similar to English. There are exceptions and contexts where it can be used interchangeably but arguably the same is true for English.

                • gambiting 9 hours ago ago

                  >>Nobody would say „trujący wąż”

                  No? That's how I've always said it. "Ta żmija jest trująca" - don't see any issue here. Jadowity grzyb I'll agree.

                  • gtech1 6 hours ago ago

                    This is fascinating, assuming you are both natives of Poland. Is there as much language variance in Poland as in, say, Italy ?

              • thaumasiotes 7 hours ago ago

                > The point is, both are correct(afaik) while in English venom and poison are definitely two different things.

                No, the situation in English matches your description exactly: all of these things are called poison. The word venom is almost never used in natural speech.

                Furthermore, if you ask English speakers what the difference between poison and venom is, by far the two most common responses will be "there isn't one" and "I don't know". icyfox is just looking to be annoying.

                (Another popular option will probably be "it's called venom when you're talking about snakes", which explains roughly 100% of use of venom in natural speech.)

    • VanshPatel99 a day ago ago

      TIL. I always thought that "If it bite you -> you die = venom" and "If you eat, bite, touch -> you die = poison". But your differentiation makes more sense

      • zahlman a day ago ago

        That explains the words "venomous" and "poisonous" used of creatures.

        It's different for the actual substances. Although it relates: a venomous creature that bites you will release its venom into your bloodstream.

        • anonym29 17 hours ago ago

          >a venomous creature that bites you will release its venom into your bloodstream

          unless it's a bee, wasp, hornet, scorpion, stingray, jellyfish, man-of-war, platypus, lionfish, stonefish, sea urchin, or catfish, which all have venom instead of poison, but the delivery mechanism of said venom isn't biting

          • zahlman 3 hours ago ago

            I said "bite" echoing the comment I was replying to. Obviously the same applies, mutatis mutandis, to stinging etc.

      • hearsathought 3 hours ago ago

        If a venomous snake bites you, you die. If you bite a venomous snake, you live. If a poisonous snake bites you, you will. If you bite a poisonous snake, you die.

        Or Hamlet's mother died by drinking poisoned wine. Hamlet died by being stabbed with an envenomed sword.

    • throwaway5465 12 hours ago ago

      Not overly pedantic at all as it highlights that by using venom the hunters were able to eat what they shot.

    • hyrix a day ago ago

      These chemicals are derived from plants where even pedants would classify them as poisons.

      The genus name Boophone is from the Greek bous = ox, and phontes= killer of, a clear warning that eating the plant can be fatal to livestock.

      • cluckindan 9 hours ago ago

        Huh, so telephone is killer of distance and Persephone is killer of… Persians? Grain? Vegetation?

        • stared 9 hours ago ago

          You're mixing up phōnē (voice) and phonos (slaughter), but the truth about Persephone is actually more metal.

          Her name predates Greek contacts with Persians, so the timeline doesn't fit. Instead, it comes from perthein (to destroy) + phonos, making her the "Bringer of Destruction". With a caveat that the etymology of her name is uncertain: https://en.wikipedia.org/wiki/Persephone#Name

          I do like "killer of distance" for telephone, though. :)

          • thaumasiotes 4 hours ago ago

            > Instead, it comes from perthein (to destroy) + phonos, making her the "Bringer of Destruction". With a caveat that the etymology of her name is uncertain:

            But... of all the theories listed there, perthein isn't among them.

            And if the roots are "destroy" and "death", what would make her the "bringer" of destruction?

      • icyfox a day ago ago

        Fair point about the source, but the classification usually follows the mode of delivery, not the organism of origin.

        Many plant-derived compounds function as venoms once introduced into the bloodstream (arrow coatings, darts, etc.), even if they’re also toxic when ingested. Curare is one example of a plant-based compound - lethal in blood, but largely harmless if eaten.

        So while Boophone is absolutely a poison in the ecological sense, using it on arrows still fits the venom/toxin distinction better than a purely ingested poison. Otherwise why would people hunt with this if they got sick the second they ate the meat?

        • jeltz 11 hours ago ago

          Is it really? We call it poison darts when hunters use poison from the poison dart frog to hunt.

    • Retric 18 hours ago ago

      In practice the difference is mostly semantics.

      Venom is still almost always poisonous when eaten and poison is harmful when injected. 2-3% as dangerous when eaten vs injected only helps so much.

    • Gud 9 hours ago ago

      Not pedantic, two different.

      Thanks for clarifying.

    • OptionOfT 18 hours ago ago

      But eating a rattlesnake and dying is a bad way of finding out that you have a stomach ulcer.

    • jeltz 11 hours ago ago

      I am not a native speaker but I believe you are wrong. It is called poison dart for example. So injected toxins can be both called poisons and venoms.

      • mrleinad 7 hours ago ago

        In Spanish it's commonly "dardo venenoso" (venomous dart), no "dardo ponzoñoso" (poisonous dart). So it's probably incorrectly used in English.

  • gilleain a day ago ago

    The poisions?

    Buphanidrine : https://pubchem.ncbi.nlm.nih.gov/compound/Buphanidrine

    and

    Epibuphanisine https://pubchem.ncbi.nlm.nih.gov/substance/349793761

    which are nearly identical compounds (it seems) except for one having an additional -OMe (Methylether) group. Looks like they are https://en.wikipedia.org/wiki/Crinine (s)

    From the https://en.wikipedia.org/wiki/Boophone_disticha plant.

    • CGMthrowaway a day ago ago

      > having an effect akin to that of scopolamine

      The motion sickness patch? Gives "just shoot me" a new meaning in 6,000 BC

      • temp0826 a day ago ago

        That is not the only effect of scopolamine. It's a very potent deliriant. In Colombia it has been used by attackers (referred to as "devil's breath", blown into the face) to cause amnesia and a very docile state (a victim might be walked to an ATM, forced to empty their accounts, and not remember a thing. Or worse). It can cause some extreme types of hallucinations.

        • gus_massa a day ago ago

          Is there a verified case? There is a similar urban legend here in Argentina, sometimes the steal your money, sometimes a kidney, ...

          • temp0826 20 hours ago ago

            There was a NYT article[0] and a few others the last few years

            [0] https://www.nytimes.com/2024/01/23/world/americas/colombia-d...

            • gus_massa 19 hours ago ago

              From your comment:

              > referred to as "devil's breath", blown into the face

              I've read similar reports in email chains in the 2000. Like the guy that touched a piece of paper and a few seconds later collapsed. I think that some local newspaper even published it, without evidence.

              From the NYT article:

              > She carried it from a restaurant counter to their table. He had two spoonfuls, Mr. Valdez, 31, said. “And that’s the last thing I remember.”

              > He drank a pink soda, he said in a video, and later awoke to find his wallet and phone gone.

              > One 42-year-old man from New York recalled being drugged by a Tinder date who served him a rum and coke that he said knocked him out for 24 hours.

              These case makes more sense. There are a few recent similar cases here, and many buildings have security cameras on the front door, so they get a nice video of the escaping thieves.

              • temp0826 17 hours ago ago

                Yah I think there's a lot of urban legend around the stuff. I know a few people who have used it (well, Brugmansia plants that contain it anyways) as part of their apprenticeships (Amazonian plant medicine, in conjunction with ayahuasca) in a more controlled manner and even then they have some wild stories about it (waking up naked in the jungle, covered in scratches with no memory etc). It lasts a looong time.

      • ChrisMarshallNY a day ago ago

        > 6,000 BC

        58,000 BC

  • ojo-rojo a day ago ago

    It's humbling to think about all the things people have gone through over the past couple hundred thousand years. Somewhere around 117 billion humans have ever lived...? It makes it seem kind of small when we think only 50 or 100 years out when thinking of what the future would be.

  • Modified3019 20 hours ago ago

    The linked study (the summary is both more concise and informative): https://www.science.org/doi/10.1126/sciadv.adz3281

  • WillAdams a day ago ago

    How was it determined that these are arrowheads, as opposed to atlatl darts?

    The oldest known/discovered/documented bows only go back to ~7,000 BC (Holmegaard bows from Northern Europe).

    • chrneu a day ago ago

      Can't directly answer your questions, but generally each region/time period has their own style of arrowheads, so my assumption here would be that this region tends to create arrowheads in this style. The paper mentions this is a pretty old site/artifacts, so I'd wager they found other "arrowheads".

      Arrowhead might also be being used generically here to mean sharpened stone tip on a projectile or thrown weapon.

      I'm no expert in this area, but it may just be that we aren't sure if these are arrowheads or just sharpened stones that were put on something. Someone correct me if I'm being ignorant. The article really makes it seem like a lot is unknown here, since we're dealing with 60,000 years.

      • Twiin a day ago ago

        There are a number of ways they're able to tell the difference between arrowheads and sharpened stones put on a stick, including high-resolution CT to look at the stress microcracks of the arrowhead. Bow-fired arrows and thrown spearheads have different launch stress profiles as well as impact profiles. There are a lot of overlapping types of analysis that happen to establish what technology did or did not exist in a given area at a given time.

    • narag a day ago ago

      You can throw the arrow with just a piece of rope rolled around your hand and using the same grip as in the atlatl. Romans called those slingshot arrows tragulae.

  • shevy-java a day ago ago

    Man has a rather unkind history.

    The even worse thing is that in 2026 this hasn't quite improved significantly. What is the main poison used today? I guess that may depend on the definition, probably particles being taken in by the lung in general. But specific poison it may be antifreeze? Or perhaps that is just more famous. Food poisoning probably is among the highest, but it would not be deliberate usually, so it should be counted in another category.

    • jayzalowitz a day ago ago

      the main poison used today is dopamine.

    • regularization 21 hours ago ago

      It was almost certainly used for agriculture. Observation of hunter-gatherer bands in modern times, and archeology have little in the way of skirmishes or warfare prior to the agricultural revolution 10,000 years ago. Not that it never happened, but violence and war are much more endemic to the modern (past 10000 years) era.

      • WalterBright 21 hours ago ago

        > violence and war are much more endemic to the modern (past 10000 years) era.

        Given the scantiness of any evidence 10,000+ years ago, I doubt such conclusions can be drawn.

      • kjkjadksj 4 hours ago ago

        Even chimpanzees engage in war and wanton violence. One would assume this behavior is at least as ancient as the most recent common ancestor we have with the chimpanzee.

  • bookofjoe 21 hours ago ago
  • adolph a day ago ago

    For context, this is towards the end of prehistoric human time period Middle Paleolithic [0] and in the middle of geological time period Late Pleistocene [1].

    0. https://en.wikipedia.org/wiki/Middle_Paleolithic

    1. https://en.wikipedia.org/wiki/Late_Pleistocene